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It is extremely rare bone disease. In this terrifying disease muscles tendons, ligaments etc turned into bone. In this disease bone begins to originate in place of connective tissue. Autosomal dominant allele in chromosome is responsible for this terrible disease. In maximum cases the unnatural mutation in gametes is the main cause behind this. The people who are suffering with FOP have no children. This disease generally happens to see 1(one) man among 2 million people. The transmutation in the gene ACVR1 is also liable for this disease. The children who have born with FOP have big toes probable no joint. It is a genetic disease and the growth of the bone during this disease starts from the top of the downward. The bone started to grow from neck, shoulder gradually chest arms etc. There are several instances available across the glove of this disease since 1800s.Harry Eastlake is the victim of this disease. His body had completely ossified and he was died in 1973.He donated his body ...

Harlequin Ichthyosis is one of the most mysterious diseases of the world.  It is also called “HARLEQUIN BABY”. It is popularly known as a skin disease. It happens due to the thickening of Keratin in human skin. Due to this disease the skin contains massive diamond shapes and skin takes reddish color. Due to this disease eyes, ear and penis increase abnormally. It is easily attracted by bacteria and it causes infection. Harlequin type generally appears in baby’s face and the serious hyperkeratosis helps to cause diamond shape in skin. It causes serious facial deformities. Ear and nose do not develop normally or some time remain abolish .Eyelid remain everted and the mouth often remain open due to this disease. Due to this disease finger, feet etc always remain in a deform state. Fingers and toes develop abnormally. These are generally abnormal in size. This type of patients cannot grab thing properly. It causes respiratory problem in them . Genetic testing is the most progressive t...

Progeria is one of the most dreadful genetic diseases of the Earth. The modern word Progeria has been taken from the Greek “Progeros” which indicates “Premature old”. The Greek word ‘Pro’ define ‘before’ and ‘geras’ indicates ‘old age’ This disease was first presented before the world by Dr.Jonathan Hutchinson in 1886 and Dr. Gilford in 1897 and with their names the disease has been given such name as HGPS. This fatal disease has different symptoms. The early signs of aging are big symptoms of this disease. Besides there are many syndrome prevailing of this disease such as decreasing of growth, short size, loss of body fat , fall of hair, cardio and heart disease , stiffness in joint area, stroke etc . Among every 4 to 5 billion newborn babies, one baby is affected by this disease in UK. The countries like Argentina, Israel, Armenia, and Austria. Canada, Australia, England etc have already reported the vicious impact of progeria. The Progeria affected patients do not live long and the...

The tree bark skin disorder is a dreadful disease. This disease gradually transfigures the human skin in tree like gesture.  It is said that this terrifying disease is incurable still now. This disease naturally happens to see in one (1) among 600000 people. It mutates one's skin into tree bark. In the past life soldiers often inserted tree’s barks, darts, worms and other organic material into their skin so that they could be a part of their environment and to make themselves hide from enemy. The Mongols in Asia, the Huns in Europe and the Vandals in African soldiers always used this process.   The tree man like syndrome concept has been going on from the past. In the past people were inserted various vermin, insects in their skin intentionally and from then tree man syndrome relation is prevailing. This future intentional exploitation is the present causes of this disease.The Human Papillomavirus physically case this disease.It starts with a single warts and cotinued the pro...

Elephantiasis is a vicious disease in this world. This disease indicates the thickening of tissues at the lower part of the body especially in legs. This disease is caused by filariasis. This disease helps to swell the tissue of the lower parts of the body. Elephantiasis has given a threat to a billion of people over 80 countries. At least 120 million of people have already came under its direct effects and among them 40 million people are in very critical condition. Effects of these diseases are increasing all over the world rapidly. It has stretched the callous steps in all the major countries of the world and in India the situation is going out of control. People are affected in elephantiasis disease due to a kind parasite such as WUCHERERIA BANCROFTI, BRUGIA MALAYI etc. This parasite is carried by mosquitoes. An initiative has been taken to eradicate the lymphatic filariasis. A report says at least 6.6 billion children have been rescued from being affected of these diseases and the...

Photo Credit : www.100toplist.com Joseph is one of the most extreme facial tumors ever seen in medical history as reported by 100toplist . The 51-year-old, from Portugal, is in danger of being suffocated by it, unless it undergoes radical surgery. Unemployed, he is blind in one eye as a result of the giant weeping growth that has consumed his features, the tumor has taken over his mouth and his tongue, balloon lips, twisting his gums and breaking his teeth off. The deep, 15cm long growth – which started as a birth mark when he was just 11 – was sparked by abnormalities in his capillaries and veins. It started to get much bigger when he hit 16 and has expanded since. He recently flew to the UK to discuss the possibility of surgery to remove part of the tumor. But because his mother was a Jehovah’s Witness, he refused any surgery because his religion means he can not receive blood transfusions. Doctors in London came up with a plan to remove parts of the growth bit by bit – without tra...