Skip to main content

THE HUTCHINSON AND GILFORD PROGERIA SYNDROME

By
Progeria is one of the most dreadful genetic diseases of the Earth. The modern word Progeria has been taken from the Greek “Progeros” which indicates “Premature old”.

The Greek word ‘Pro’ define ‘before’ and ‘geras’ indicates ‘old age’

This disease was first presented before the world by Dr.Jonathan Hutchinson in 1886 and Dr. Gilford in 1897 and with their names the disease has been given such name as HGPS.
This fatal disease has different symptoms. The early signs of aging are big symptoms of this disease. Besides there are many syndrome prevailing of this disease such as decreasing of growth, short size, loss of body fat , fall of hair, cardio and heart disease , stiffness in joint area, stroke etc .

Among every 4 to 5 billion newborn babies, one baby is affected by this disease in UK. The countries like Argentina, Israel, Armenia, and Austria. Canada, Australia, England etc have already reported the vicious impact of progeria. The Progeria affected patients do not live long and these types of patients generally die between the ages of 8 to 21.

Progeria leads to release” Lamin A” protein and this protein helps the nucleus to be unstable.This instability accelerate the process of aging. Most of the physician affirmed that Progeria is not a hereditary disease. It is found that progeria syndromes pass to one generation to another in about 1 in 100 cases.
Progeria can be recognized through genetic test or by watching the symptoms
FITS (FARNESYLTRANSFERASE) might give a new structure to the unstable nucleus which supposed to be the main cause of progeria.  An FITS testing was taken among 13 mice and only one was died of 105 days UCLA study.
“This study gives us pieces of information critical to our movement toward clinical trials in children with progeria."-spoken by Dr. Leslie Gordon.
But what is most unfortunate is that there is no special treatment available in the universe for this dreadful disease.
Labels:

Comments

Post a Comment

Popular posts from this blog

AYE AYE :THE BAD LUCK OMEN

By
Aye Aye is one of the rarest animals of the world. It belongs to the mammals groups. This rare creature dwells in globular nest which has a small hole to enter and exit. When this creature rides on the tree, it uses its middle finger to tap the tree. It uses its slender finger to find out the taste insects. Aye Aye also uses the same middle finger to lift out insects. Its eyes and ears are unusually large. Due to its big eyes some consider this creature as the demon. These types of creatures are very sensitive. These rare creatures are generally found in the Madagascar Island.  The native islanders of Madagascar often killed this creature in first sight because they believe this creature as evil omen. Aye Aye are the only primates of the mammal world to depend on echolocation for pursue.But the most astonishing fact is that this species is in great danger. These animals are particularly fond of ceramicist beetle. They even eat insects, nectar, seeds etc. Aye Aye are dark/brown or ...
Post a Comment
Read more

THE MYSTERIOUS DISEASE HARLEQUIN ICHTHYOSIS

By
Harlequin Ichthyosis is one of the most mysterious diseases of the world.  It is also called “HARLEQUIN BABY”. It is popularly known as a skin disease. It happens due to the thickening of Keratin in human skin. Due to this disease the skin contains massive diamond shapes and skin takes reddish color. Due to this disease eyes, ear and penis increase abnormally. It is easily attracted by bacteria and it causes infection. Harlequin type generally appears in baby’s face and the serious hyperkeratosis helps to cause diamond shape in skin. It causes serious facial deformities. Ear and nose do not develop normally or some time remain abolish .Eyelid remain everted and the mouth often remain open due to this disease. Due to this disease finger, feet etc always remain in a deform state. Fingers and toes develop abnormally. These are generally abnormal in size. This type of patients cannot grab thing properly. It causes respiratory problem in them . Genetic testing is the most progressive t...
Post a Comment
Read more

THE RARE FIBRODYSPLASIA OSSIFICANS PROGRESSIVA

By
It is extremely rare bone disease. In this terrifying disease muscles tendons, ligaments etc turned into bone. In this disease bone begins to originate in place of connective tissue. Autosomal dominant allele in chromosome is responsible for this terrible disease. In maximum cases the unnatural mutation in gametes is the main cause behind this. The people who are suffering with FOP have no children. This disease generally happens to see 1(one) man among 2 million people. The transmutation in the gene ACVR1 is also liable for this disease. The children who have born with FOP have big toes probable no joint. It is a genetic disease and the growth of the bone during this disease starts from the top of the downward. The bone started to grow from neck, shoulder gradually chest arms etc. There are several instances available across the glove of this disease since 1800s.Harry Eastlake is the victim of this disease. His body had completely ossified and he was died in 1973.He donated his body ...
Post a Comment
Read more