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THE RARE FIBRODYSPLASIA OSSIFICANS PROGRESSIVA

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It is extremely rare bone disease. In this terrifying disease muscles tendons, ligaments etc turned into bone. In this disease bone begins to originate in place of connective tissue.
Autosomal dominant allele in chromosome is responsible for this terrible disease.
In maximum cases the unnatural mutation in gametes is the main cause behind this. The people who are suffering with FOP have no children. This disease generally happens to see 1(one) man among 2 million people. The transmutation in the gene ACVR1 is also liable for this disease.
The children who have born with FOP have big toes probable no joint. It is a genetic disease and the growth of the bone during this disease starts from the top of the downward. The bone started to grow from neck, shoulder gradually chest arms etc.

There are several instances available across the glove of this disease since 1800s.Harry Eastlake is the victim of this disease. His body had completely ossified and he was died in 1973.He donated his body with the hope to find any solution for this extremely cruel disease. There are 700 cases of FOP across the globe.




There is no curable treatment of this disease in this universe. Though surgical attempt may be little bit helpful but the anesthesia patients may face difficulties. Scientist once discovered that squalamine can be fruitful to treat the patients who are suffering from FOP.Squalamine is generally found from shark and it has the properties of antibiotic.

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